International Transporter Consortium (ITC) Workshop 3 – Transporters in Drug Development Pre-conference
Monday, March 13, 2017 – Tuesday, March 14, 2017
Transporters play key roles in human physiology and pathophysiology, contributing to the absorption, distribution, metabolism and excretion of structurally- and pharmacologically-diverse drugs.   Research on membrane transporters has exploded, with approximately half of all scientific research articles on transporters published within the last 10 years.  Increasingly, drug developers and regulatory scientists are interested in transporters as mediators of clinically important drug-drug interactions, and as pharmacologically relevant targets.  The International Transporter Consortium (ITC) has played a key role in informing regulatory policy through careful and critical evaluation of published research. The ITC continues to be a leader in this area in sponsoring and organizing the ‘Third Workshop on Membrane Transporters in Drug Development’.  In this two-day Pre-conference, participants will hear lectures from world-class transporter biologists from universities, regulatory agencies and pharmaceutical companies.  These lectures cover a range of topics in transporter biology, including the endogenous function of transporters, emerging transporters of importance in drug development, computational modeling, genomics and biomarker probes of transporters.  The workshop concludes with a session focusing on regulatory issues in transporter-mediated drug-drug interactions, with case studies representing perspectives of regulatory agencies (e.g., FDA and EMA) as well as a panel discussion involving experts in the field to address questions from the attendees.

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Clinical Pharmacogenetics Implementation Consortium (CPIC) 2017 Conference: Using Pharmacogenetic Tests in Patient Care
Wednesday, March 15, 2017 Registration for the CPIC Pre-conference is sold out.
The one-day Pre-conference is organized by the Clinical Pharmacogenetics Implementation Consortium (CPIC®) ( as part of the Pharmacogenomics Research Network (PGRN) ( The meeting is open to all and features presentations from world-class speakers who will describe current examples of implementation of pharmacogenomics in the clinic. There will also be panel discussions to summarize topics and encourage audience participation. Presentations will include “best cases” as well as challenging cases for implementation, and will include international perspectives on clinical use of pharmacogenomics. CPIC® is one of the enabling resources funded by the National Institutes of Health as part of the Pharmacogenomics Research Network, and is a shared project between PharmGKB ( and the PGRN. The mission of the PGRN is to catalyze and lead research in precision medicine for the discovery and translation of genomic variation influencing therapeutic and adverse drug effects. CPIC’s goal is to facilitate translation by overcoming some of the barriers to implementation of pharmacogenetic tests into clinical practice. Over 180 CPIC members from 19 countries participate to develop tools to facilitate clinical implementation of pharmacogenetics, primarily by developing freely available, peer-reviewed, updatable, and detailed gene/drug clinical practice guidelines.

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