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Showcase of Top Trainee Abstracts
Wednesday, March 15 | 4:30pm – 5:30pm

ASCPT is proud to honor the top scoring abstracts submitted by clinical pharmacologists in training. These Presidential Trainee Award recipients will be recognized during the Showcase of Top Trainee Abstracts on Wednesday, March 15 from 4:30 pm- 5:30 pm. Posters will be on display during poster sessions on Wednesday, Thursday and Friday.

These videos highlight the exceptional research of the Presidential Trainee Award recipients.



COMPARISON OF NON-COMPARTMENTAL ANALYSIS (NCA) ESTIMATION AND POPULATION PHARMACOKINETIC (PPK) PREDICTIONS OF EXPOSURE CHANGES AS A FUNCTION OF RENAL IMPAIRMENT.
Mariam Ahmed
University of Minnesota
   

CLINICAL IMPLEMENTATION OF WARFARIN PHARMACOGENETICS IN A REAL-WORLD SETTING: A PROPOSAL FOR A NEW PHARMACOGENETIC DOSING APPROACH FOR DIVERSE PATIENT POPULATIONS.
Meghan Arwood, PharmD
University of Florida
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DATA-DRIVEN LEARNING ANALYSIS IDENTIFIES GENDER DIFFERENCES IN METABOLIC TREATMENT RESPONSE OF CITALOPRAM/ESCITALOPRAM IN MAJOR DEPRESSIVE DISORDER.
Arjun Athreya
University of Illinois at Urbana-Champaign
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RESULTS OF THE IMPLEMENTATION OF PHARMACOGENOMICS INTO PRIMARY CARE PROJECT
Paul Bank, PharmD
Leiden University Medical Centre
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A GENETIC VARIANT OF ABCG2 CONFERS RISK FOR POOR RESPONSE TO ALLOPURINOL INDEPENDENT OF ITS EFFECT ON GOUT SEVERITY.
Deanna Brackman
University of California San Francisco
   

MAN1A2 IS A NOVEL PREDICTIVE MARKER OF REFRACTORY RESPONSE TO R-CHOP THERAPY IN DIFFUSE LARGE B-CELL LYMPHOMA.
Matthew Breitenstein, PhD
Mayo Clinic
   

IN VITRO AND IN VIVO FUNCTIONAL TESTING OF SNPS IN THE 3'UTR OF CYP2B6.
Kimberly Burgess
Indiana University School of Medicine
   

TACROLIMUS POPULATION PHARMACOKINETICS AND CYP3A5 GENOTYPES IN AFRICAN AMERICAN AND CAUCASIAN RENAL TRANSPLANT RECIPIENTS.
Olivia Campagne, PharmD             
University at Buffalo, SUNY
   

RNA-SEQ ANALYSES IDENTIFY MOLECULAR MARKERS OF BLOOD PRESSURE (BP) RESPONSE TO THIAZIDE DIURETICS (TD).
Ana Caroline Costa Sa
University of Florida
   

AGGREGATE BOTTOM-UP PBPK MODELS FOR DRUG EXPOSURE INDIVIDUALLIZATION.
Jean Dinh, PharmD, PhD
Children's Mercy Hospital
   

DISCOVERY OF SUBSTRATES FOR GLUT2, A TRANSPORTER IMPLICATED IN METFORMIN RESPONSE.
Jessica Enogieru
University of California San Francisco
   

AGE-DEPENDENT DEVELOPMENTAL CHANGES IN HEPATIC ORGANIC CATION TRANSPORTER 1 (OCT1) PROTEIN EXPRESSION IN NEONATES AND SMALL INFANTS.
David R. Hahn, PhD
Cincinnati Children's Hospital Medical Center
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TCL1A IDENTIFICATION AS A NOVEL TRANSCRIPTION FACTOR AND A PHARMACOGENOMIC LINK TO AROMATASE INHIBITOR-INDUCED MUSCULOSKELETAL ADVERSE EVENTS.
Ming-Fen Ho, PhD
Mayo Clinic
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INTACT NEPHRON THEORY MAY NOT FULLY EXPLAIN THE EFFECT OF SEVERE RENAL IMPAIRMENT FOR DRUGS ACTIVELY SECRETED VIA RENAL ORGANIC ANION TRANSPORTERS.
Chia-Hsiang Hsueh, PhD
US Food and Drug Administration
   

AN EXEMPLAR OF A SYSTEMS PHARMACOLOGY APPROACH FOR A DETAILED INVESTIGATION OF AN ADVERSE DRUG EVENT AS A RESULT OF DRUG-DRUG INTERACTIONS.
Sarah Kim, PhD
University of Florida
Vew video
   

ORGANIC CATION TRANSPORTER 1 (OCT1; SLC22A1) MODULATES HEPATIC ENERGY METABOLISM.
Xiaomin Liang
University of California, San Francisco
   

UGT1A9 RS3832043 INFLUENCES ACETAMINOPHEN GLUCURONIDATION IN NEONATES.
Matthew W. Linakis
University of Utah
   

MATERNAL AND FETAL METHADONE EXPOSURE: ASSOCIATIONS WITH NEONATAL ABSTINENCE SYNDROME.
Ingrid F. Metzger, PhD
Indiana University School of Medicine
   

HUMAN MICRODOSING AND MICE XENOGRAFT DATA OF AGM-130 APPLIED TO SIMULATE EFFICACIOUS DOSES IN PATIENTS.
Wan-Su Park
The Catholic University of Korea
   

COMMON GENETIC VARIANTS IN NEUROBEACHIN (NBEA) ARE ASSOCIATED WITH METFORMIN DRUG RESPONSE IN INDIVIDUALS WITH TYPE 2 DIABETES IN THE ACCORD CLINICAL TRIAL.
Daniel Rotroff, PhD
North Carolina State University
   

THIAZIDE INDUCED HYPERURICEMIA: NOVEL INSIGHTS FROM METABOLOMICS AND GENOMICS INTEGRATION IN THE PHARMACOGENOMIC EVALUATION OF ANTIHYPERTENSIVE RESPONSES 2 (PEAR 2) STUDY.
Mohamed H. Shahin, PhD
University of Florida
   

DEVELOPMENT OF A PHARMACOKINETIC (PK)/PHARMACODYNAMIC (PD) MODEL TO EVALUATE THE IMPACT OF PK VARIATION ON PD FOR EXTENDED RELEASE METOPROLOL FORMULATIONS.
Vishnu D. Sharma, PhD
University of Florida
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A GENOME WIDE ASSOCIATION STUDY IDENTIFIES PHARMACOGENOMIC VARIANTS ASSOCIATED WITH CHLORTHALIDONE INDUCED GLUCOSE CHANGE IN AFRICAN AMERICANS.
Sonal Singh, PhD

University of Florida 
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COMPARISON OF THE EFFECT OF CHRONIC KIDNEY DISEASE (CKD) ON PHARMACOKINETICS OF CYP1A2, CYP2C8, CYP2C9 AND CYP2C19 SUBSTRATES.
Ming-Liang Tan, PhD
US Food and Drug Administration
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IMAGING ANTIRETROVIRAL DISTRIBUTION WITHIN GASTROINTESTINAL TISSUES ACROSS PRE-CLINICAL SPECIES: IMPLICATIONS FOR HIV ERADICATION.
Corbin Thompson, PharmD
University of North Carolina at Chapel Hill
   

FEASIBILITY OF A PEDIATRIC MICRODOSE STUDY OF [14C]MIDAZOLAM TO STUDY THE ONTOGENY OF CYP3A-MEDIATED DRUG METABOLISM.
Bianca van Groen, PharmD
Erasmuc MC - Sophia Children's Hospital
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MATURATION OF HUMAN HEPATIC MEMBRANE TRANSPORTER PROTEINS IN THE FIRST FOUR MONTHS OF LIFE.
Bianca van Groen, PharmD
Erasmus MC - Sophia Children's Hospital



EXCIPIENTS INHIBIT HUMAN ORGANIC ANION TRANSPORTING PEPTIDE 2B1 (OATP2B1)-MEDIATED INTESTINAL UPTAKE OF LEVOTHYROXINE.
Ling Zou, PhD
University of California, San Francisco





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