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CPT:PSP Tutorials

Tutorials are educational articles providing practical tutorial on tools, methodologies, and approaches in pharmacometrics and systems pharmacology. Tutorials aim to increase the awareness and potential of pharmacometrics and systems pharmacology outside the disciplines, introduce methodology to newcomers interested in model-based approaches, and provide further training and specialized guides to those already working in the field.

All content published by CPT:PSP is Open Access and made freely available to readers worldwide. Read all of the Tutorials published by CPT:PSP by clicking here.

 2012  |  2013  |  2014  |  2015  |  2016  |  2017 

2017
Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics OPEN

Building confidence in quantitative systems pharmacology models: An engineer's guide to exploring the rationale in model design and development OPEN

2016
Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model OPEN

Understanding the Behavior of Systems Pharmacology Models Using Mathematical Analysis of Differential Equations: Prolactin Modeling as a Case Study OPEN

A Six-Stage Workflow for Robust Application of Systems Pharmacology OPEN

Communicating to Influence Drug Development and Regulatory Decisions: A Tutorial OPEN

Good Practices in Model-Informed Drug Discovery and Development (MID3): Practice, Application and Documentation OPEN

A Model Qualification Method for Mechanistic Physiological QSP Models to Support Model-Informed Drug Development OPEN

2015
A tutorial on RxODE: Simulating differential equation pharmacometrics models in R OPEN

The many flavours of model based meta-analysis: Part I - Introduction and Landmark data OPEN

Agent based modeling in systems pharmacology OPEN

Use of Modeling and Simulation in the Design and Conduct of Pediatric Clinical Trials and the Optimization of Individualized Dosing Regimens OPEN

Establishing Good Practices for Exposure-Response Analysis of Clinical Endpoints in Drug Development
 OPEN

MatVPC: A User-friendly Matlab-based Tool for the Simulation and Evaluation of Systems Pharmacology Models OPEN

Cloud Computing for Pharmacometrics: Using AWS, NONMEM, PsN, Grid Engine and Sonic OPEN

A Tutorial on Target-Mediated Drug Disposition (TMDD) Models OPEN

Quantifying and Communicating Uncertainty in Preclinical Human Dose-Prediction OPEN

Interactive Pharmacometric Applications Using R and the Shiny Package OPEN

BioModels: Content, Features, Functionality, and Use OPEN

Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology Models OPEN

Developing Exposure/Response Models for Anticancer Drug Treatment: Special Considerations OPEN

2014
Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development OPEN

Modeling and Simulation of Count Data OPEN

Exposure–Response Modeling of Clinical End Points Using Latent Variable Indirect Response Models OPEN

Visualization and Communication of Pharmacometric Models With Berkeley Madonna OPEN

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development: Part 3—Introduction to Pharmacodynamic Modeling Methods OPEN

2013
Editorial: Pharmacometrics and Systems Pharmacology Software Tutorials and Use: Comments and Guidelines for PSP Contributions OPEN

Application of ggplot2 to Pharmacometric Graphics OPEN

Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development OPEN

Editorial: Tutorials on the Foundations of Pharmacometrics and Systems Pharmacology OPEN

Establishing Best Practices and Guidance in Population Modeling: An Experience With an Internal Population Pharmacokinetic Analysis Guidance OPEN

Modeling and Simulation Workbench for NONMEM: Tutorial on Pirana, PsN, and Xpose OPEN

A Time to Event Tutorial for Pharmacometricians OPEN

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development—Part 2: Introduction to Pharmacokinetic Modeling Methods OPEN

2012
Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development OPEN


 2012  |  2013  |  2014  |  2015  |  2016 

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