CPT:PSP is pleased to offer our own podcast, PSPod. Join us as we delve into advances in quantitative methods as applied in pharmacology, physiology and therapeutics in humans.
As an online-only, Open Access journal, all content is made freely available to readers worldwide immediately upon publication. All CPT:PSP papers are indexed in PubMedCentral. Read all of the CPT:PSP articles here.
In this episode, Drs. Scott Marshall from Pfizer, Sandra Visser from Merck, and Amy Cheung from AstraZeneca discuss "Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation": Their White Paper published in the March issue of PSP. You can get free access the White Paper by clicking here.
February 2016: Communicating Systems Pharmacology and Pharmacometric Models
In this episode, Peter Bonate from Astellas, discusses effective communication in systems pharmacology and pharmacometric models. You can read a review of Dr. Bonate's book Be a Model Communicator and Sell your Models to Anyone, reviewed by Ellen Leinfuss in the May 2015 issue, by clicking here.
January 2016: Existing Practice and Modeling Approaches and Future Directions for Modeling to Assess and Predict Cardiovascular Liabilities of New Drugs
This episode features Sandra Visser and Anne Chain from Merck & Co/MSD, discussing existing practice and modeling approaches and some thoughts with regard to future directions for modeling to assess and predict cardiovascular liabilities of new drugs. You can read Dr. Visser's Review "Implementation of Quantitative and Systems Pharmacology in Large Pharma" by clicking here.
September 2015: The Drug Disease Model Resources (DDMoRe): A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
This episode features Lutz Harnisch from Clinical Pharmacology Pharmacometrics at Pfizer, discussing the Drug Disease Model Resources (DDMoRe) consortium. His Perspective article that introduces the activities of the DDMoRe consortium can also be found here.
June 2015: Databases as tools in pharmacometrics and systems pharmacology
In this episode, we interview Dr. Shiew-Mei Huang, Deputy Director, Center for Drug Evaluation and Research at the Food and Drug Administration about a drug interaction database--a tool for evaluating the impact of renal or hepatic impairment in a pharmacologic inhibition on the systemic exposure of drugs. Read the article here.
March 2015: Infectious diseases and the role of pharmacometrics
In this episode, we interview Dr. Steven E. Kern, Deputy Director of Quantitative Sciences at the Bill and Melinda Gates Foundation, about infectious diseases in context of the possibilities for pharmacometrics and systems pharmacology to contribute to improve treatments in the area.
November 2014: Predictive systems pharmacology in pediatrics
In this episode, Geoff Marsh interviews Catherijne Knibbe, PharmD, PhD, from St. Antonius Hospital about modeling and simulation in pediatric clinical oncology. Listen to the full podcast here.
August 2014: Systems Pharmacology Approaches in Oncology
In this episode, Geoff Marsh interviews Dr. James M. Gallo, PharmD, PhD, from The Mount Sinai Hospital, about the application of systems pharmacology approaches to oncology. Listen to the full podcast here.
May 2014: PBPK Modeling
In this podcast, Geoff Marsh interviews Dr. Amin Rostami, PharmD, PhD, of the University of Manchester, about the recent resurgence of physiologically based pharmacokinetic (PBPK) modeling in systems pharmacology. Listen to the full podcast here.
February 2014: Diabetes
In this podcast, Geoff Marsh interviews Dr. Vijayalakshmi Chelliah, PhD, the lead curator of Biomodels Database, at the EMBL- European Bioinformatics Institute about the impact of mathematical modeling on the understanding of diabetes and related complications. Listen to the full podcast here.
November 2013: Tutorials
In this podcast, Geoff Marsh interviews Dr. Diane Mould, PhD, of Projections Research about Tutorials, a new series of articles published in CPT: Pharmacometrics &Systems Pharmacology. Tutorials serve as important educational material on the tools, methodologies, and approaches used for modeling and simulation. Listen to the full podcast here.