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CPT: Pharmacometrics & Systems Pharmacology (CPT:PSP) is an online-only, open-access journal devoted to publishing advances in quantitative methods as applied in pharmacology, physiology, and therapeutics in humans. All content published in CPT:PSP is Open Access and thus freely accessible to readers worldwide immediately upon publication.  Check out the latest research published in CPT:PSP this month:

Tutorial
Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics OPEN

Building confidence in quantitative systems pharmacology models: An engineer's guide to exploring the rationale in model design and development OPEN

Articles
Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults OPEN

Development and qualification of physiologically based pharmacokinetic models for drugs with atypical distribution behavior: A desipramine case study OPEN

AFIR: A Dimensionless Potency Metric for Characterizing the Activity of Monoclonal Antibodies OPEN

Population Pharmacokinetics of Selumetinib and Its Metabolite N‐desmethyl‐selumetinib in Adult Patients With Advanced Solid Tumors and Children With Low‐Grade Gliomas OPEN

Evaluating Dosage Optimality for Tofacitinib, an Oral Janus Kinase Inhibitor, in Plaque Psoriasis, and the Influence of Body Weight OPEN

Reviews
Towards Quantitative Systems Pharmacology Models of Chemotherapy‐Induced Neutropenia OPEN


Perspective
Implementing Genomic Clinical Decision Support for Drug-Based Precision Medicine OPEN

Editorial
Precision Medicine in Pharmacometrics and Systems Pharmacology OPEN


Database
Database of Optimized Proteomic Quantitative Methods for Human Drug Disposition‐Related Proteins for Applications in Physiologically Based Pharmacokinetic Modeling OPEN

Letters to the Editor
Response to “Quantitative Prediction of Drug‐Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is It Worth?” OPEN

Time of the Day and Magnitude of the Effect of a Drug on the QTc Interval OPEN

Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth ItOPEN

New content is published online daily at the Wiley Online Library

 

 


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