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CPT Clinical Trials

Clinical Pharmacology & Therapeutics considers manuscripts developed from well-conducted, well-reported, and relevant clinical trials. If advanced for consideration, manuscripts can be elected for rapid review and potential fast-track publication. Submission requirements for clinical trials are provided in the Clinical Trials Guide.

CPT will consider clinical trials that report on original phase II/III results of hypothesis testing randomized controlled trials for pharmaceuticals, prespecified subgroup analyses of previously published randomized trials (emphasis on pharmacogenetic/genomic, and exposure-response) subgroup/responder analyses, phase IIa/IIb dose-ranging trials (exposure response analyses), original Proof of Concept (POC) randomized controlled trials, and randomized withdrawal trials in any phase of development.

The journal offers both expedited review and advance online publication for select clinical trial submissions. Authors of clinical trials may also opt for Open Access publication. Open access articles will also be deposited on PubMed Central at the time of publication and will be freely available immediately to researchers worldwide. 

Read some of the recently published Clinical Trials in CPT
:
Batch-to-batch pharmacokinetic variability confounds current bioequivalence regulations: A dry powder inhaler randomized clinical trial

Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood–Brain Barrier


An accessible pharmacodynamic transcriptional biomarker for notch target engagement


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