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Top Cited CPT Papers


2011 Year-to-date
 Title Author  Article Typle   Volume
Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies D J Angiolillo  Article  89.1
The Emerging Role of Electronic Medical Records in Pharmacogenomics R A Wilke  State of the Art  89.3
Clinical Pharmacogenetics Implementation Consortium Guildelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing     M V Relling  Article  89.3
CPIC: Clinical Pharmacogenetics Implemenation Consortium of the Pharmacogenomics Research Network M V Relling  Practice  89.3
Pharmaceutical Innovation in the 21st Century: New Drug Approvals in the First Decade, 2000-2009 K I Kaitin State of the Art  89.2
The Use of Induced Pluripotent Stem Cells in Drug Development I Inoue State of the Art  89.5
Common Nonsynonymous Substitutions in SLCO1B1 Predipose to Statin Intolerance in Routinely Treated Individuals with Type 2 Diabetes: A Go-DARTS Study L A Donnelly  Article  89.2
Estrogen Receptors: Therapies Targeted to Receptor Subtypes S Nilsson State of the Art  89.1
Refining the Benefit-Risk Framework for the Assessment of Medicines: Valuing and Weighting Benefit and Risk Parameters S Walker Conference Proceedings  89.2
Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review P Zhao  Article  89.2



2010
Title Author  ArticleType Volume 
Obesity, Inflammation, and Cardiovascular Risk P Mathieu
State of the Art 87.4
Genetic Factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) Are
Predictor Variables for Warfarin Response in Very Elderly, Frail
Inpatients
E Pautas
Article     87.1
Precompetitive Research: A New Prescription for Drug
Development?
J Woodcock
Macroscopy  87.5
Cancer and Inflammation: Implications for Pharmacology and
Therapeutics
F Balkwill
State of the Art 87.4
Deconstructing the Drug Development Process: The New Face of
Innovation
K Kaitin 
Development  87.3
Optimization of Initial Tacrolimus Dose Using Pharmacogenetic
Testing
E Thervet
Article 87.6
The Critical Path Institute's Approach to Precompetitive Sharing
and Advancing Regulatory Science
R Woosley
Commentary 87.5
Transporter Pharmacogenetics and Statin Toxicity
M Niemi 
Practice 87.1

2009
Title Author  ArticleType Volume 
Pharmacogenetics of neonatal opioid toxicity following
maternal use of codeine during breastfeeding: a case-control study
P Madadi Article 85.1
Risk of myocardial infarction and death associated with the nonsteroidal anti-inflammatory drugs (NSAIDs) among health individuals: a nationwide cohort study EL Fosbøl Article     85.2
Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia G Stocco Article 85.2
Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus B Komoroski Article 85.5
Dose-response of ritonavir on hepatic CYP3A activity and elvitegravir oral exposure AA Mathias Article 85.1
Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects B Komoroski Article 85.5
Pharmacoepigenetics: its role in interindividual differences in drug response A Gomez Discovery    85.4
Safety assessment and dose selection for first-in-human clinical trials
with immunomodulatory monoclonal antibodies
PY Muller State of the Art 85.3
New antithrombotic drugs P L Gross State of the Art 85.2

2008
Title Author  Article Type Volume
Influence of CYP2C9 and VKORc1 1173C/T on the risk of hemorrhagic complications in African-American and European-American patients on warfarin N Limdi Article 83.2
CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: A prospective randomized controlled study Y Caraco Article 83.3
Cathepsin K inhibitors: a novel target for osteoporsis therapy SA Stoch Development 83.1
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics Y Shu Article 83.2

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