Read CTS Now

Clinical and Translational Science (CTS), an online-only, open access journal that highlights original research that helps bridge laboratory discovery with the diagnosis and treatment of human disease. Research may appear as Full Articles, Commentaries, Point-Counterpoint, Phase Forward (Clinical Trials), or Reviews. CTS also includes invited didactic content that covers the connections between clinical pharmacology and translational medicine. These additional features provide context for research articles and facilitate understanding for a wide array of individuals interested in clinical and translational science. 
Check out the latest research published in CTS:

Influence of OATP1B1 Function on the Disposition of Sorafenib‐β‐D‐Glucuronide OPEN

Exploratory Analysis of Associations Between Postmarketing Safety Events and Approved Doses of New Drugs in Japan OPEN

Phase Forward
A Phase I Randomized Study of a Specifically Engineered, pH-Sensitive PCSK9 Inhibitor RN317 (PF-05335810) in Hypercholesterolemic Subjects on Statin Therapy OPEN

Pharmacokinetics, Safety, and CCR2/CCR5 Antagonist Activity of Cenicriviroc in Participants With Mild or Moderate Hepatic Impairment OPEN

A Study on CYP2C19 and CYP2D6 Polymorphic Effects on Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Koreans

The Role of Next-Generation Sequencing in Enabling Personalized Oncology Therapy OPEN

Translating Precision OPEN

In Pursuit of Greater Reproducibility and Credibility of Early Clinical Biomarker Research OPEN

Early Vision for the CTSA Program Trial Innovation Network: A Perspective from the National Center for Advancing Translational Sciences OPEN

Microphysiological Systems (“Organs‐on‐Chips”) for Drug Efficacy and Toxicity Testing OPEN

Intra‐Target Microdosing (ITM): A Novel Drug Development Approach Aimed at Enabling Safer and Earlier Translation of Biological Insights Into Human Testing OPEN

Clinical Pharmacology and Translational Aspects of Bispecific Antibodies OPEN

The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real‐World Setting OPEN

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