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ASCPT

2015-2020 | STRATEGIC PLAN

TRANSFORMING TRANSLATION

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MISSION STATEMENT

Advancing clinical pharmacology, translational medicine and therapeutics for the benefit of patients and society.

VISION STATEMENT

ASCPT’s influence and leadership make it the authority on the science and practice of translational medicine, building on a foundation of clinical pharmacology and therapeutics.

CORE PRINCIPLES

  • Clinical pharmacology and translational medicine drive the development and use of therapeutics to enhance patient care.
  • The continuum of clinical pharmacology and translational medicine strengthens the discovery, development, regulation, as well as safe and effective utilization of medications.
  • The unique strength of ASCPT lies in its multi-disciplinary nature and its ability to be a catalyst for emerging science.
  • ASCPT demonstrates the highest standards of ethics and integrity and fosters these values with a commitment to diversity.

GOALS

  • SCIENTIFIC EXPERTISE
    ASCPT unifies therapeutic disciplines, convening translational scientists in academia, industry and government to leverage their diverse expertise.
  • CATALYST FOR INNOVATION
    ASCPT fosters innovation and is at the forefront of emerging scientific fields in clinical pharmacology and translational medicine.
  • INFLUENCE AND IMPACT
    ASCPT is the scientific resource that influences decision-making on therapeutic usage for patient care.
  • EDUCATION AND COMMUNICATION
    ASCPT builds upon its exceptional educational offerings and family of journals to create value for members and new audiences.
  • ORGANIZATIONAL EFFECTIVENESS
    ASCPT has the infrastructure to sustain its leadership position in the field, secure a strong financial future, and support diversity in its evolving membership.

DEFINITION OF
TRANSLATIONAL MEDICINE

TO SUPPORT ASCPT STRATEGIC PLAN IMPLEMENTATION

Implementation of the ASCPT Strategic Plan will be guided by a broad and inclusive description of translational medicine to reflect the diversity of scientific disciplines involved in translational research within our Society. For the purpose of this document, translational research, translational science and translational medicine will be used interchangeably with a unifying principle that the ultimate purpose is to improve human health via a “bench to bedside” approach. There are many definitions of translational medicine as well as translational science and translational research, which provide context for ASCPT’s efforts. John Hutton1 defines translational research as “Research [that] transforms scientific discoveries arising from laboratory, clinical or population studies into new clinical tools and applications that improve human health by reducing disease incidence, morbidity and mortality.” Another perspective2 is “Translational research fosters the multidirectional integration of basic research, patient-oriented research, and population-based research, with the long-term aim of improving the health of the public.”

From ASCPT’s perspective, translational medicine is a multi-faceted discipline with a focus on translational therapeutics. In a broad sense, translational medicine bridges across the discovery, development, regulation, and utilization spectrum. It may include application of research findings from genes, proteins, cells, tissues, organs, and animals, to clinical research in patient populations, all aimed at optimizing and predicting outcomes in specific patients. For clinical pharmacology, the focus of translational research is on the discovery, development, regulation and use of pharmacologic agents to improve clinical outcome, and inform optimal use of therapeutics in patients. In addition, translational research in clinical pharmacology may include evaluation of various biomarkers of pharmacologic response and assessing the linkage between biomarker response and clinical endpoints in patients. Our broad description also includes how the response to a therapeutic intervention in a particular disease may translate to a response in another disease, as well as translation of safety signals across species and/or patient populations. Translational research is bolstered by quantitative, model-based and mechanistic understanding of disease biology and pharmacology. Consequently core disciplines, including clinical pharmacology, pharmacogenomics, systems pharmacology, precision medicine, as well as others play an integral role in enabling translational research and translational medicine.


1 Wang X. A new vision of definition, commentary, and understanding in clinical and translational medicine. Clinical and Translational Medicine 2012;1:5.
2 Rubio DM et al. Defining translational research: Implications for training. Acad Med. 2010;85:470-5.

ASCPT 2015-2020
STRATEGIC PLANNING TASK FORCE

Richard Lalonde, PharmD, Chair
John A. Wagner, MD, PhD, President
Antoinette Ajavon, PhD
Kathleen M. Giacomini, PhD
Dan Hartman, MD
Anne C. Heatherington, PhD
Sean Hennessy, PharmD, PhD
Julie A. Johnson, PharmD
Lang Li, PhD
Donald E. Mager, PharmD, PhD

Min Soo Park, MD, PhD
Kellie Schoolar Reynolds, PharmD
Mario L. Rocci, Jr., PhD
Michelle A. Rudek, PharmD, PhD
Virginia (Ginny) D. Schmith, PhD, FCP
Valentina Shakhnovich, MD
Aubrey Stoch, MD
Pieter H. van der Graaf, PhD, PharmD
Satsuki Yamada, MD, PhD