ASCPT News, November 29, 2018

Published on 11/29/2018 6:00:00 AM

Secure Your Early Bird Savings and Snake Pit Participation Now!
December is almost here, which means that Early Bird registration for the March 2019 Annual Meeting will soon be gone and time is running out to register your team for the Snake Pit: Grant Me the Money! challenge!

Don’t miss your opportunity to secure the Early Bird registration rate for the March 13-16, 2019, Annual Meeting in Washington, DC. Rates will increase on December 14, 2018, so register soon! Details on the outstanding scientific program are available here. Once you register, use the housing links provided in your registration confirmation email to secure your housing at the official Annual Meeting hotels, the Washington Hilton for anyone who needs housing for the night of Tuesday, March 12, 2019, and the Washington Marriott Park Hotel for the full conference dates. The ASCPT housing block will fill quickly, so don’t wait!

Looking for a way to actively participate in the 2019 Annual Meeting and possibly secure some funding for your research? Review the guidelines for participating in the Snake Pit: Grant Me the Money! challenge, then register your team by the December 14, 2018, deadline. This special session will test your skills in presenting a research proposal, with the top proposals to be selected for live presentation at the Annual Meeting and grant money to be awarded by the participating agencies after the meeting! 

Questions about Annual Meeting registration, housing, or participation in the Snake Pit: Grant Me the Money! session can be sent to meetings@ascpt.org
Join Us for the Next Members-Only Webinar
Join the Pharmacogenomics (PGx) Community at 2:00 PM EST on December 10, 2018, as they present Functional Annotation of Variants of Uncertain Significance

Kiran Musunuru, MD, PhD, MPH, will describe an approach based on induced pluripotent stem cells (iPSCs) to functionally annotate variants of uncertain significance in cardiomyopathy-associated genes. The platform makes use of CRISPR-Cas9 and other gene-editing tools to rapidly insert or correct patients’ variants in iPSCs, followed by differentiation of the iPSCs into cardiomyocytes in a dish. Various properties of these cardiomyocytes can provide insight into whether the variants are benign or pathogenic. The approach has been used for annotation of patients’ variants in TNNT2 and LMNA and has been developed to the point that it can be used to inform patient management in real time. 

To register or for more information, please visit the ASCPT Webinar Resources page. 

Connect With the ASCPT Journal Family
Read posts on Translational Bytes and PSPost, browse journal content on the app, or attend the upcoming CPT webinar!  

PSP Launches New Virtual Issue 
Significant challenges are posed by rare diseases and the development of treatments for them. In the latest PSPost, France Mentré, MD, PhD, and Piet van der Graaf, PhD, PharmD, highlight some of those challenges and introduce a new collection of articles from CPT: Pharmacometrics & Systems Pharmacology (PSP). Read A Unique Collection of State-of-the-Art Pharmacometric and Systems Pharmacology Approaches in Rare Diseases Pharmacology and Therapeutics today. 

A Look at Chimeric Antigen Receptor T-Cell Therapy
In Translational Bytes, Clinical and Translational Science (CTS) Associate Editor Mark Dresser, PhD, examines the recently published Commentary Chimeric Antigen Receptor T‐Cells: Successful Translation of the First Cell and Gene Therapy From Bench to Bedside, from Rodriguez-Cartagena, et al., which provides a comprehensive summary of the scientific advancements and regulatory pathways that led to the approval of the first CAR T-cell therapies. Don't miss Here in My CAR(T)!

ASCPT Journal Family Content Direct to Your Device
Access the ASCPT Journal Family anywhere with the Clinical Pharmacology & Therapeutics (CPT), PSP, and CTS mobile apps. Stay current with the latest articles on Early View, save favorite articles for quick and easy retrieval, and browse issues before you download them, all via your smartphone or tablet! You can also opt in to receive alerts when new issues are available. Download the CPT, PSP, and CTS apps today from the Apple App Store.

Mark Your Calendar 
There’s still time to sign up – register today! 

Title: 2018 ITC Update on Clinically-Relevant Transporters, Clinical Probes, and DDI Evaluation
Date and Time: December 7, 2018 12:00 PM EST
Speakers: Maciej Zamek-Gliszczynski, PhD
Moderator: Shuiying Hu, PhD
Description: Join this ASCPT Journal Family webinar as Maciej Zamek-Gliszczynski, PhD, summarizes the state-of-the-art in transporters in drug development based on four recent ITC whitepapers recently published in Clinical Pharmacology & Therapeutics (Vol 104, Iss 5). A practical overview of emerging transporters of clinical relevance will be provided (e.g., OCT1, OATP2B1, etc.). Best practice in design of clinical DDI studies will be illustrated with recent advances in the study of OCT1, P-gp, and BCRP. Lastly, considerations for optimal selection of clinical probe drugs, including future potential utility of transporter biomarkers, will be discussed.
Register Today! 

#GivingTuesday May Have Passed, but the Season to Give Continues!
ASCPT thanks our members who participated in the #GivingTuesday challenge and reminds you that this global day of giving is just one effort to raise funds for student/trainee travel grants.

ASCPT is grateful for your contributions that will allow the Society to provide students and trainees who will be presenting abstracts at the 2019 Annual Meeting with travel grants to help cover their costs for participating. As you consider your year-end giving, please consider making a contribution to this important effort. Log into your member dashboard on www.ascpt.org today and click Donate to make a contribution.  

Career Center Feature Alert! 
Did you know that the ASCPT Career Center shows you jobs similar to what you’re currently viewing and searching for right at the bottom of the page?

It’s true! Search for your desired job in clinical pharmacology, translational medicine or therapeutics and you’ll also see recommendations given to you on the bottom of the screen.

This functionality will pull up to four similar jobs based on the job search performed or the job being viewed. This feature gives you a better job search experience by allowing you to see more relevant jobs you may be interested in. Get Started Today!

Here are some of the most recently posted positions:
Scientific Director, Quantitative Clinical Pharmacology (Neuroscience)
Scientist - B-Cell Immunology
Research Associate- Immunology
Associate Scientist/Scientist Drug Metabolism
Scientist, In Vivo Pharmacology Image-Guided Radiotherapy
Academic Pediatric Allergy/Immunology Physician

ASCPT Welcomes the following New Members to the Society: 

Amer Al-khouja, PhD

Vanessa Baier, MSc 

S. Eralp "Al" Bellibas, MD, PhD

Tjerk Bueters, PhD   

Richard Dixon, MS, MSc          

Jin Dong, PhD         

Allison Garcia

Stan Hartman, MD    

Andrew Heitman, MS

Yitao Jiang, None     

Aditya Reddy Kolli, PhD           

Maayan Leroy-Melamed, MD     

Yassine Kamal Lyauk, MSc       

Marissa Mackiewicz, PhD, RN   

Erik Mannaert, PharmD, PhD    

Amanda Mantua, BS 

Nseobong Ntukidem, MD         

Bukola Odeniyi, BSc

Neven Mohamed Abdalla Sarhan, MSc      

Sari Shiba, MS         

Thomas Van Looy, PhD            

Laurens Verscheijden, MSc       

Hao Xiong, MBA, PhD              

Wangda Zhou, PhD  

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