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Translational & Precision Medicine Network

Network Goals

Scientific Expertise:
  • The TPM Network and associated Communities facilitate interactions between experts across multidisciplinary fields to foster translational science with a focus on individuals via patient care and society via healthcare. The interactions are through social media, email blasts, and teleconferences with focused scientific content.
Catalyst for Innovation:
  • The TPM Network is a catalyst for innovation by sponsoring a range of scientific programs at the Annual Meeting focused on translational and precision medicine.
Influence and Impact:
  • The TPM Network is the lead group engaged in translational and precision medicine and optimal pharmacotherapy in patient care.
Education and Communication:
  • The TPM Network offers educational opportunities via the Communities.
Organizational Effectiveness:
  • Leadership within TPM is expanded by a Network Steering Committee.
  • The TPM Network has regularly scheduled teleconferences and utilizes social media to engage members throughout the year.
  • The TPM Network fosters the career of its members by assisting Communities in recognizing members for individual achievements and contributions to ASCPT, sponsoring educational programming in translational and precision medicine, and providing opportunities for networking activities throughout an individual’s career.

ASCPT 2018 Annual Meeting
Translational & Precision Medicine (TPM) Network Meeting 
WEDNESDAY, MARCH 21, 2018, 1:00 pm-3:00 pm
Room: Florida 5
Join the TPM Network for a brief business meeting followed by two talks: "Genome-Wide Association Study of Antipsychotic Pharmacokinetics," present ed by Kristin L. Bigos, PhD, and "Precision Medicine with Indigenous People," presented by Erica Woodahl, PhD. The meeting will close with a discussion and programming strategy session and a presentation on "What's Next on the Horizon in Precision Medicine," presented by Kelly E. Dooley, MD, PhD, and Matthew L. Rizk, PhD.

Upcoming Community Webinars
Joint Systems Pharmacology and Biomarkers & Translational Tools Community Webinar
Title
: Quantitative Systems Pharmacology (QSP) Modeling of Drug-Induced Nephrotoxicity – Bridging the Link Between Drug Exposure, Urinary Biomarkers and Renal Dysfunction
Date and Time: Friday, February 16, 2018, 12:00 PM EST
Speakers: Yeshitila Gebremichael, PhD, Scientist, DILIsym Services., Inc.
Moderators: Richard Graham, PhD, Senior Director, Theravance Biopharma and BTT Community Chair
Description: Drug-induced nephrotoxicity is a challenging problem in both drug development and clinical treatment of critically ill patients. Detecting the potential for nephrotoxicity early in the drug development process is vital for safe development and dosing of therapies. Many novel urinary biomarkers that are injury-specific and more sensitive than traditional biomarkers have been identified recently, whereas interpretation remains challenging. Furthermore, a quantitative framework that links biomarkers signals to underlying cellular injury and renal dysfunction is lacking. Such framework plays a crucial role in safe drug development and clinical treatment. By coupling observations from preclinical urinary biomarkers and histopathology data with cell biology, renal physiology, and the physiologic processes involved in biomarker expression, we developed a multiscale quantitative systems pharmacology (QSP) model of drug-induced acute kidney injury.
To register, please visit the Biomarkers & Translational Tools community page

Joint Infectious Diseases and Global Health Community Webinar
Title:  Breaking Down Barriers for Acceleration of Development of New Anti-Infectives
Date and Time: Wednesday, February 21, 2018, 1:00 PM EST
Speakers: Major Jeffrey W. Froude, II, PhD, Uniformed Services University of the Health Sciences and Steven E. Kern, PhD, Bill and Melinda Gates Foundation
Moderators: Kelley E. Dooley, MD, PhD, Johns Hopkins University School of Medicine, and Matthew Rizk, PhD, Merck

Organizer: Hazem Hassan, PhD, MS, RPh, RCDS, University of Maryland School of Pharmacy
Description: This webinar will focus on the integrated research and development methods utilized by the Department of Defense for acquiring medical countermeasures.  Major Jeff Froude will discuss historical success of the therapeutic developments by DTRA during the Ebola outbreak and how these lessons learned can be utilized in the future  for both defense threats as well as global health countermeasure development. Dr. Kern will discuss how the Gates Foundation is working with their partners to use model-informed drug development techniques to advance the development of anti-infective agents in global health.  With specific emphasis on malaria, tuberculosis, and other neglected diseases, this section will highlight challenges to new drug development for these conditions and opportunities being implemented that address these challenges and improve the potential for creating successful therapeutic solutions.
Registration Link:
 https://register.gotowebinar.com/register/3791315492349279233

Past Webinars
Visit the Member-Exclusive Webinar Library
TPM Network Member Interview Series
coming soon

Joan Korth Bradley, PharmD, PhD

Network Chair

Read her bio.

Kathryn Momary, PharmD, BCPS

Network Vice Chair

Read her bio.

Michelle A. Rudek, PharmD, PhD

Network Past Chair

Read her bio.

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