Upcoming Webinars:

ASCPT Pharmacometrics & Pharmacokinetcs (PMK) Community Members-Only Webinar
Title:  Marrying Real-World Data and Modeling: A Case of Interdisciplinary MIDD to Address Changes of Bone Mineral Density in Premenopausal Women
Date and Time: Friday, August 14, 2020, 11:00 am ET
Speaker: Mohamad Shebley, PhD
Moderators: Chunze Li, PhD, and Akshanth Polepally, PhD
Description: This webinar will introduce the concept of interdisciplinary model-informed drug development (i-MIDD) in a real drug development setting. The presented work will describe how real-world data (RWD) could be linked to traditional pharmaco-statistical modeling to bridge understanding of long-term bone safety in premenopausal women. The work will highlight how the RWD could be extended to epidemiological modeling for evaluating clinical relevance of the projected changes in bone mineral density (BMD) in relation to future risk of bone fractures. For additional information, please click the registration link below.
Registration Link: https://us02web.zoom.us/webinar/register/WN_7eQ1iOZSQL6hQIHQSScsCg

ASCPT Early Career (EC) Community and Oncology (ONC) Community Members-Only Webinar:
Title: Translational and Clinical Pharmacology Considerations in the Development of Immune-Oncology Drugs
Date and Time: Friday, August 28, 2020, 2:00 pm ET
Speaker: Sree Kasichayanula, PhD
Moderators: Pooja Manchandani, PhD, and Malek Okour, PhD
Description: The presentation will highlight the hallmarks of immuno-oncology drug development and expand on pharmacometrics, clinical pharmacology and statistical strategies to optimize clinical trial design and development of immune-oncology drugs. This will be the first webinar of a three-part series on immune-oncology drug development. Highlights of this session will include:

• Fundamental biology underpinnings and trajectory of immune-oncology drug development and how this differs from the standard clinical development paradigm in oncology.
• Role and impact of clinical pharmacology aspects to support immune-oncology drug development for monotherapy and combination.
• Modeling and simulation strategies and clinical trial designs for early development and pivotal trials.

Registration Link: https://us02web.zoom.us/webinar/register/WN_LHbb5WQqQfeRoRDSW8wwTg

ASCPT Early Development & Drug Safety (EDDS) and Oncology (ONC) Communities Members-Only Webinar
Title: Using Preclinical Data in Phase I Oncology Trials: A Bayesian Decision-Theoretic Approach
Date and Time: Tuesday, September 1, 2020, 11:00 AM ET
Speaker: Haiyan Zheng, PhD
Moderator: Huiming Xia, MSc, PhD
Description: Using preclinical data to specify a prior for the human dose-toxicity model parameter(s) can improve interim dose recommendations and precision for estimating the maximum tolerated dose (MTD). Such advantages, however, must be balanced against the risk that more patients will possibly be treated with excessively toxic doses in the case of a prior-data conflict. This presentation will make a proposal for how to measure and address a prior-data conflict in a sequential study with a small sample size. For learning objectives and additional description information, please click the registration link below.
Registration Link:  https://us02web.zoom.us/webinar/register/WN_Uw-PHaVcRnuDTZwa1AfNiw

ASCPT Members-Only Webinar presented by the Infectious Diseases (INF) and Oncology (ONC) Communities
Title: Convergence of Therapeutic Approaches in Oncology and HIV to Target Immune Evasion: Integrating Clinical Pharmacology Lessons Learned
Date and Time: Friday, September 25, 2020, 12:00 pm ET
Speakers: Akintunde Bello, PhD, and Islam Younis, PhD
Moderators: Daria Stypinski, PhD, and Mark Dresser, PhD
Description: This special virtual session will bring together experts with experience in immuno-oncology and HIV research. They will address the major lessons learned from each therapeutic area and the goal to accelerate the pace and lesson the challenges of drug development. The participants will gain knowledge in the overlapping mechanisms in HIV and cancer that have made similar treatment strategies possible. Lessons learned will be shared from HIV combination therapy approaches on establishing contributions of regiment components to overall safety and efficacy. Immuno-oncology on dose-optimization challenges in the development of immune checkpoint inhibitors will also be explored.
Registration Link: https://us02web.zoom.us/webinar/register/WN_kkLBLp9nT26MkB_rW89UXQ

Past Open-Access webinars:

Title	Speaker(s)	Recording and/or Presentation Slides	Primary Audience
ASCPT Career Center Micro-Recruitment Session with the US Food and Drug Adminsitration	Doanh Tran, PhD, Deputy Director Division of Cardiometabolig and Endocrine Pharmacology Carol Ambush, Project Manager, Office of Clinical Pharmacology	Webinar Recording	ASCPT Career Center
ASCPT Career Center Micro-Recruitment Session with Certara	Julie Bullock, Vice President, Integrated Drug Development Emily Cox, Director, Talent Acquisition	Webinar Recording	ASCPT Career Center
Reviewer Readiness: How to be an Effective Reviewer for ASCPT Journals	Valentina Shakhnovic, MD Deanna Kroetz, PhD	Webinar Recording	ASCPT Journal Family CTS journal
Pediatric Master Protocols: Clinical Pharmacology Challenges and Opportunities	Luna Musib, PhD Elimika Pfuma Fletcher, PharmD, PhD Nita Seibel, MD	Webinar Recording	Special Populations Community Regulatory Science Community
Perfecting Your ASCPT Meeting Experience How to Make the Most of Your First ASCPT Annual Meeting	Brian Corrigan, PhD	Webinar Recording	ASCPT 2019 Annual Meeting
How to Develop and Qualify Biomarkers  Biomarker Consortium Perspective	Joseph P. Menetski, PhD	Webinar Recording	CTS Journal
2018 ITC Update on Clinically-Relevant Transporters, Clinical Probes, and DDI Evaluation	Maciej Zamek-Gliszczynski, PhD	Webinar Recording	CPT Journal
Endogenous Biomarkers of Membrane Transporters and Model Based Prediction of Clinic	Kenta Yoshida, PhD Xinning Yang, PhD	Webinar Recording	PSP Journal
ASCPT Abstracts – Everything You Need to Know	Kellie Schoolar Reynolds, PharmD	Webinar Recording Webinar Transcript	Annual Meeting
Member Orientation Webinar Sponsored by Cytel	Jin Yan Jin, PhD	Webinar Recording	ASCPT New Members
New Member Welcome	Jin Yan Jin, PhD	Webinar Recording	ASCPT New Members
2018 Scientific Proposals - Secrets to Success	Virginia (Ginny) D. Schmith, PhD, FCP	Webinar recording	ASCPT Members
New Member Welcome Webinar for 2017 Annual Meeting Attendees	Jin Yan Jin, PhD	Webinar Recording	New ASCPT Members
How to Participate in the ASCPT 2017 Annual Meeting		Webinar Recording	Membrane Transporter
Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics	France Mentré	Webinar Recording	ASCPT Journal Family
Driving Patient-Centered Translational Medicine	Christopher P. Austin, MD	Webinar Recording	ASCPT Journal Family
Implementing Pharmacogenetic Tests for Patient Care Using Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guidelines	Mary V. Relling, PharmD	Webinar Recording	ASCPT Journal Family
Journal Club "Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes"	Wenjian Yang	Webinar Recording *presentation only, no audio Presentation slides	Pharmacogenomics
Pharmacokinetics and Dose Adjustments for Monoclonal Antibodies in IBD - Considerations and Applications in Clinical Practice	Diane Mould, PhD Anne Strik, MD	Webinar Recording Presenters' responses to attendee questions	ASCPT Journal Family

For all past webinars please visit the ASCPT Webinar Library.