Online Education

ASCPT is pleased to offer complimentary access to live and recorded educational resources, as a benefit to its members.  You must be logged in as a member to view these materials.

Upcoming Webinars:
ASCPT Journal Family Webinar
: Changes in Expression and Activity of Transporters in Disease: Do They Impact Pharmacokinetics and Toxicity of Drugs?
Date and Time: November 29, 2018 12:00 PM EST
Speakers: Raymond Evers, PhD, and Jason Sprowl, PhD
Moderator: Saskia de Wildt, MD, PhD
Description: Transporters play a critical role in the ADME of many drugs and endogenous compounds. Disruption of these pathways can have a profound effect on overall physiology, or drug pharmacokinetics, efficacy, and toxicity. Join Drs. Evers and Sprowl as they provide an overview of changes in transporter function associated with acute and chronic disease states, and regulatory pathways affecting transporter expression. In addition, they will discuss how mechanistic understanding in the role of transporters in drug disposition can aid in alleviating transporter-mediated toxic effects.
Registration Link: https://attendee.gotowebinar.com/register/5869984011849709313

ASCPT Journal Family Webinar
Title: 2018 ITC Update on Clinically-Relevant Transporters, Clinical Probes, and DDI Evaluation
Date and Time: December 7, 2018 12:00 PM EST
Speakers: Maciej Zamek-Gliszczynski, PhD
Moderator: Shuiying Hu, PhD
Description: Join this ASCPT Journal Family webinar as Maciej Zamek-Gliszczynski, PhD summarizes the state-of-the-art in transporters in drug development based on four recent ITC whitepapers recently published in Clinical Pharmacology & Therapeutics (Vol 104, Iss 5). A practical overview of emerging transporters of clinical relevance will be provided (e.g., OCT1, OATP2B1, etc.). Best practice in design of clinical DDI studies will be illustrated with recent advances in the study of OCT1, P-gp, and BCRP. Lastly, considerations for optimal selection of clinical probe drugs, including future potential utility of transporter biomarkers, will be discussed.
Registration link: https://attendee.gotowebinar.com/register/4318986521719019011 

Past webinars:
 Title Speaker(s) Recording and/or Presentation Slides Primary Audience
Endogenous Biomarkers of Membrane Transporters and Model Based Prediction of Clinic Kenta Yoshida, PhD
Xinning Yang, PhD
 Webinar Recording PSP Journal
ASCPT Abstracts – Everything You Need to Know Kellie Schoolar Reynolds, PharmD Webinar Recording
Webinar Transcript
Annual Meeting
Member Orientation Webinar Sponsored by Cytel
Jin Yan Jin, PhD Webinar Recording ASCPT New Members
New Member Welcome Jin Yan Jin, PhD Webinar Recording
Presentation Slides
ASCPT New Members
2018 Scientific Proposals - Secrets to Success Virginia (Ginny) D. Schmith, PhD, FCP Webinar recording
Presentation Slides
 ASCPT Members
New Member Welcome Webinar for 2017 Annual Meeting Attendees
Jin Yan Jin, PhD
Webinar Recording
Presentation Slides

New ASCPT Members
How to Participate in the ASCPT 2017 Annual Meeting
  Webinar Recording
Membrane Transporter
Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics France Mentré
Webinar Recording ASCPT Journal Family
Driving Patient-Centered Translational Medicine
Christopher P. Austin, MD
Webinar Recording
ASCPT Journal Family
Implementing Pharmacogenetic Tests for Patient Care Using Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guidelines
Mary V. Relling, PharmD
Webinar Recording
ASCPT Journal Family
Journal Club "Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes"
Wenjian Yang Webinar Recording
*presentation only, no audio
Presentation slides
Pharmacokinetics and Dose Adjustments for Monoclonal Antibodies in IBD - Considerations and Applications in Clinical Practice
Diane Mould, PhD
Anne Strik, MD
Webinar Recording
Presenters' responses to attendee questions 
ASCPT Journal Family

For all past webinars please visit the ASCPT Webinar Library.

Upcoming Webinars:
ASCPT Members-Only Webinar Presented by the Pharmacogenomics Community (PGx)
Title: Functional annotation of variants of uncertain significance
Date and Time: 2:00 PM EST, Monday, December 10, 2018 
Speakers: Dr. Kiran Musunuru
Moderator: Dr. Sonal Singh
Description: The presentation will describe an approach based on induced pluripotent stem cells (iPSCs) to functionally annotate variants of uncertain significance in cardiomyopathy-associated genes. The platform makes use of CRISPR-Cas9 and other gene-editing tools to rapidly insert or correct patients’ variants in iPSCs, followed by differentiation of the iPSCs into cardiomyocytes in a dish. Various properties of these cardiomyocytes—such as morphological and electrophysiological characteristics—can provide insight into whether the variants are benign or pathogenic. The approach has been used for annotation of patients’ variants in TNNT2 and LMNA and has been developed to the point that it can be used to inform patient management in real time. A specific example regarding a 65-year-old woman with hypertrophic cardiomyopathy and a variant of uncertain significance in TNNT2, which was successfully annotated between her first and second clinic visits and had implications for cascade genetic testing of her children and grandchildren, will be highlighted.
Registration: https://attendee.gotowebinar.com/register/5191457794941374978

Check back for more information about ASCPT Replay.

ASCPT thanks the members of its Webinar Committee for its efforts in developing strong, meaningful informational and educational materials, which are accessible to ASCPT members in an online format. Submit your idea for a webinar.

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  • ASCPT Members-Only Webinar Presented by the Pharmacogenomics Community (PGx)
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