Upcoming Webinars:

ASCPT Pharmacometrics & Pharmacokinetcs (PMK) Community Members-Only Webinar
Title:  Effective Visual Communication for Quantitative Scientists, 2-Part Series
Part 2 Date and Time: Friday, January 22, 2021, 11:00 am ET
Speakers: Mark Baillie, PharmD, Baldur Magnusson, PhD, Alison Margolskee, PhD, and Marc Vandemeulebroecke, PhD
Moderator: Neeraj Gupta, PhD
Description: Effective visual communication (EVC) is a core competency for all scientists who work with data, such as pharmacologists, pharmacometricians, statisticians, data scientists, etc. By using the right graphical principles, we can better understand data, highlight core insights, and influence decisions toward appropriate actions. Without them, we can mislead others and ourselves and pave the way to wrong conclusions and actions.
The aim of this 2-part webinar is to provide a deep dive into EVC for quantitative scientists through a series of case studies and exercises, focusing on the key principles of purpose, clarity, and message. Format of the 2-part webinar:

• Part 1: Presenters will provide an overview of EVC principles and walk through case studies applying a structured approach to creating an effective visualization, and introduce hands-on examples for homework for Part 2
• Homework: Between Parts 1 and 2, participants are asked to apply the structured approach to improve a graph or to visualize a dataset and submit their work prior to Part 2 for discussion.
• Part 2: Facilitators will discuss hands-on examples (homework) introduced in Part 1 with EVC principles in mind. Some attendees may be invited to participate as panelists to discuss their approach. Attendees can participate by providing comments through chat functionality.

Part 1 Resources: Presentation Slides; Graphic Principles Webinar
Part 2 Registration Link: https://us02web.zoom.us/webinar/register/6216040086160/WN_54ufx8UnRa6UWyRJTVtPeQ

ASCPT Members-Only Webinar Presented by the Special Populations (SPO) Community
Title:  Ethnic Diversity and Drug Response: Drug Development Consequences
Date and Time: Thursday, January 21, 2021, 3:30 pm ET
Speaker: Annette Gross, PhD
Moderators: Elimika Pfuma Fletcher, PharmD, PhD, and Pooja Manchandani, PhD
Description: This presentation will provide an overview of inter-ethnic differences in drug response, inclusive of the intrinsic and extrinsic factors which can be associated with population differences in pharmacokinetics, pharmacodynamics, efficacy, and safety. Drug development considerations will be discussed in relation to potential inter-ethnic differences in drug response including relevant regulatory guidelines (e.g., ICH E5, ICH E17) and assessment of ethnic sensitivity, US Food & Drug Administration Clinical Trial Diversity initiative, requirements for clinical trial data in specific countries / ethnic groups, and implications for drug development strategies and design of clinical studies (e.g., Multiregional Clinical Trials, Bridging Studies).
Registration Link: https://us02web.zoom.us/webinar/register/3116098729528/WN_YVZtagb4TRexjOoRG3cxNg

ASCPT Members-Only Webinar Presented by the Membrane Transporter (MT) Community
Title:  Proteomics-Informed Prediction of Transporter-Enzyme Interplay in Drug Disposition
Date and Time: Wednesday, January 27, 2021, 12:00 pm ET
Speaker: Bhagwat Prasad, PhD
Moderators: Aneesh Argikar, PhD, and Jason Sprowl, PhD
Description: Drug metabolism and transport processes are the key mechanisms of drug disposition that are often liked to drug efficacy and toxicity. While in vitro models can produce reproducible drug metabolism and transport data, in vivo translation of in vitro data are often challenging, especially when both drug transporters and metabolizing enzymes are involved. Join us for this 45-minute special presentation to learn more about the challenges of current methods as well as a proteomics-informed approach. This approach predicts the tissue-specific fractional contribution of metabolism and transport (fm or ft) by individual mechanism, which can be utilized in predicting tissue-specific drug interactions, toxicity, and efficacy. This presentation will provide examples of fm and ft prediction for testosterone and irinotecan in different tissues using the proteomics-informed approach. The approach will be further elaborated to describe the quantitative interplay between metabolism and transport for these compounds.
Registration Link: https://us02web.zoom.us/webinar/register/6616092643617/WN_auYTFk5tRGCoDD6JCvGT1Q

ASCPT Members-Only Webinar Presented by the Pharmacometrics & Pharmacokinetics (PMK) and Early Career (EC) Communities
Title:  Introduction of Deep Learning in Drug Discovery and Development
Date and Time: Thursday, January 28, 2021, 4:00 pm ET
Speaker: Jagdeep Podichetty, PhD
Moderators: Daniela Conrado, PhD
Description: Deep Learning is a machine learning technique that uses multiple layers to extract information from raw data. Neural Networks, the algorithms used in Deep Learning, are used in everything from drug candidate identification to classification of a disease state through raw images. This webinar will give an overview of the Deep Learning landscape and highlight the application of deep learning in drug discovery and development. Additionally, this webinar will discuss the framework for artificial neural networks as well as their fundamental building blocks.
Registration Link: https://us02web.zoom.us/webinar/register/1016091735567/WN_aaNADgn8Th2Gm2TFW8t3bw

ASCPT Members-Only Webinar Presented by the Pharmacometrics & Pharmacokinetics (PMK) and Regulatory Science (RS) Communities
Title: Clinical Pharmacology Considerations for Antibody Drug Conjugates
Date and Time: Friday, January 29, 2021, 1:00 pm ET
Speaker: Krithika Arun Shetty, PhD
Moderators: Bilal AbuAsal, PhD, and Chunze Li, PhD
Description: Since 2000, ten Antibody Drug Conjugates (ADCs) have been approved by the US Food & Drug Administration all for oncology indications. Several other ADC products are in various stages of development. This presentation will provide an overview of the clinical pharmacology considerations in ADC development with a focus on the utility of PK-PD modeling and simulation in the ADC drug development process and in regulatory decision making. Summaries/case examples of population PK and E-R models that have been utilized in the regulatory review, approval and labeling of current ADCs will be discussed.
Registration Link: https://us02web.zoom.us/webinar/register/1616076355147/WN_beLmdFaISS-gsi4Be0UuTQ

Past Open-Access webinars:

Title	Speaker(s)	Recording and/or Presentation Slides	Primary Audience
ASCPT Career Center Micro-Recruitment Session with the US Food and Drug Adminsitration	Doanh Tran, PhD, Deputy Director Division of Cardiometabolig and Endocrine Pharmacology Carol Ambush, Project Manager, Office of Clinical Pharmacology	Webinar Recording	ASCPT Career Center
ASCPT Career Center Micro-Recruitment Session with Certara	Julie Bullock, Vice President, Integrated Drug Development Emily Cox, Director, Talent Acquisition	Webinar Recording	ASCPT Career Center
Reviewer Readiness: How to be an Effective Reviewer for ASCPT Journals	Valentina Shakhnovic, MD Deanna Kroetz, PhD	Webinar Recording	ASCPT Journal Family CTS journal
Pediatric Master Protocols: Clinical Pharmacology Challenges and Opportunities	Luna Musib, PhD Elimika Pfuma Fletcher, PharmD, PhD Nita Seibel, MD	Webinar Recording	Special Populations Community Regulatory Science Community
Perfecting Your ASCPT Meeting Experience How to Make the Most of Your First ASCPT Annual Meeting	Brian Corrigan, PhD	Webinar Recording	ASCPT 2019 Annual Meeting
How to Develop and Qualify Biomarkers  Biomarker Consortium Perspective	Joseph P. Menetski, PhD	Webinar Recording	CTS Journal
2018 ITC Update on Clinically-Relevant Transporters, Clinical Probes, and DDI Evaluation	Maciej Zamek-Gliszczynski, PhD	Webinar Recording	CPT Journal
Endogenous Biomarkers of Membrane Transporters and Model Based Prediction of Clinic	Kenta Yoshida, PhD Xinning Yang, PhD	Webinar Recording	PSP Journal
ASCPT Abstracts – Everything You Need to Know	Kellie Schoolar Reynolds, PharmD	Webinar Recording Webinar Transcript	Annual Meeting
Member Orientation Webinar Sponsored by Cytel	Jin Yan Jin, PhD	Webinar Recording	ASCPT New Members
New Member Welcome	Jin Yan Jin, PhD	Webinar Recording	ASCPT New Members
2018 Scientific Proposals - Secrets to Success	Virginia (Ginny) D. Schmith, PhD, FCP	Webinar recording	ASCPT Members
New Member Welcome Webinar for 2017 Annual Meeting Attendees	Jin Yan Jin, PhD	Webinar Recording	New ASCPT Members
How to Participate in the ASCPT 2017 Annual Meeting		Webinar Recording	Membrane Transporter
Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics	France Mentré	Webinar Recording	ASCPT Journal Family
Driving Patient-Centered Translational Medicine	Christopher P. Austin, MD	Webinar Recording	ASCPT Journal Family
Implementing Pharmacogenetic Tests for Patient Care Using Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guidelines	Mary V. Relling, PharmD	Webinar Recording	ASCPT Journal Family
Journal Club "Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes"	Wenjian Yang	Webinar Recording *presentation only, no audio Presentation slides	Pharmacogenomics
Pharmacokinetics and Dose Adjustments for Monoclonal Antibodies in IBD - Considerations and Applications in Clinical Practice	Diane Mould, PhD Anne Strik, MD	Webinar Recording Presenters' responses to attendee questions	ASCPT Journal Family

For all past webinars please visit the ASCPT Webinar Library.