Description:

• Quantitative, system-level, mechanism-based modeling approaches to enable best decisions in drug discovery, development, and regulatory interactions.

Scientific Expertise:

• This Community is a resource for best practices in Systems Pharmacology through ‘state-of-the-art’ communication and compendium of current case examples, and through contributions to Annual Meeting programming and educational opportunities.

Catalyst for Innovation:

• The Systems Pharmacology Community is implementing a ‘hot topics’ forum listing emerging and novel methods for collaborative Community development. This forum will be hosted on the ASCPT Systems Pharmacology Community site and/or other social media site(s).

Influence and Impact:

• Our Community is initiating a compendium of clinical systems pharmacology case examples with impact statements describing how each has influenced clinical and/or regulatory-focused decisions. This compilation will include solicitation from the Community members and a literature review with a potential ‘hot topics’ forum as necessary.

Education and Communication:

• Our Community is developing an inventory of the current ‘state-of-the-art’ in Systems Pharmacology to identify areas of need as training & communication opportunities, e.g., model development and qualification standards. We also continue to develop educational opportunities around subjects identified by members of our Community.

Organizational Effectiveness:

• We are establishing a Systems Pharmacology Community Steering Committee (SC) membership along with general roles & expectations necessary to align our contributions with other Community goals. We are also establishing timings for communication outreach to Community members to announce key dates and news updates.