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Community Updates
The Membrane Transporter Community is publishing a series of white papers in Clinical Pharmacology & Therapeutics; based on topics covered in the 3rd Workshop in 2017. Papers accepted for publication are available online and collated as a themed issue of the journal in November 2018. For questions, please contact members@ascpt.org.
Past Webinars
The webinars below can be accessed in the Members Only Webinar Library:
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- Are Coproporphyrins (CP) the Only Game in Town? Jumping Into the Bile Acid Pool to Identify Non-CPI/III Biomarkers for Assessing OATP1B Mediated Drug-Drug Interactions
- Role of Transporters in Toxicity (open access) Audience Questions (pdf)
- Regulation of Drug Transport Proteins – From Mechanisms to Clinical Impact
- In Vitro-In Vivo Correlation for Drug-Drug Interactions with Rosuvastatin
- Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations
- FDA’s Final DDI Guidances What You Need to Know About Transporter DDI
- Use of Extended Clearance Concept and PBPK Modeling in New Drug Discovery and Development: Predicting Target Tissue Exposure from In Vitro to In Vivo (open access) Presentation Slides (pdf)
- Proteomics-Informed Prediction of Transporter-Enzyme Interplay in Drug Disposition
- Novel Insights into the Etiology and Treatment of Drug-Induced Peripheral Neuropathy
- Intestinal OATP mediated Drug Interactions: Where are We
- Amino Acid Transporters as Potential Targets in Cancer Therapy
Past White Papers
We encourage you to review the International Transporter Consortium (ITC) white papers below that were published in Clinical Pharmacology & Therapeutics (CPT) in 2022. To access the digital versions, please visit your Member Dashboard and click on CPT Member Access. You can then search for them by their titles.
= open access