Membrane Transporter (MT) Community

Community Goals

The Membrane Transporter (MT) is a community of scientists within the Translation and Precision Medicine Network with extensions in other scientific organizations relevant to clinical pharmacology. Our overall goal is to provide a forum for scientists from all sectors including academia, industry and regulatory agencies with expertise in transporters to share ideas that catalyze innovation in research on the role of transporters in the safe and effective use of medications in all patients. To this end, we are active participants in the ASCPT Annual Meeting and of ongoing activities throughout the year that stimulate education in transporter biology and clinical pharmacology.
Our specific goals are to:
  • Support the career development of scientists in the MT by sponsoring educational and networking events and activities to enhance our scientific expertise about transporters, and to keep abreast of innovative research in the field;
  • Propose and sponsor scientific symposia, workshops, sunrise sessions, poster sessions and other fora of discussions for the ASCPT Annual Meetings, as well as meetings of other relevant organizations, that provide members of ASCPT with information on the role of transporters in clinical pharmacology and translational medicine and therapeutics; with emerging information.
  • Support continuing educational activities by sponsoring regular webinars and other educational activities focused on the relevance of transporters in the safe and effective use of medications;
  • Stimulate networking and scientific collaborations among clinical pharmacologists with broad research interests in transporters, particularly as they pertain to translational research and precision medicine, through the Annual Meeting and other activities such as webinars.
  • Develop and facilitate interactions among the multi-disciplinary members of the MT Community, the Translation and Precision Medicine (TPM) Network, and the two other Networks, Quantitative Pharmacology (QS) and Development, Regulatory and Outcomes (DRO), through sponsoring joint events at the Annual Meeting, such as joint symposia and workshops and other sustained educational and collaborative activities.
  • Support activities of the MT in other scientific organizations that are of particular interest to ASCPT members. These activities include co-sponsorship of scientific symposia at meetings of other complementary organizations.

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Community Updates
The Membrane Transporter Community is publishing a series of white papers in Clinical Pharmacology & Therapeutics; based on topics covered in the 3rd Workshop in 2017. Papers accepted for publication are available online and collated as a themed issue of the journal in November 2018. For questions, please contact members@ascpt.org.

Past Webinars
The webinars below can be accessed in the Members Only Webinar Library: Access Library
  • Are Coproporphyrins (CP) the Only Game in Town? Jumping Into the Bile Acid Pool to Identify Non-CPI/III Biomarkers for Assessing OATP1B Mediated Drug-Drug Interactions
  • Role of Transporters in Toxicity (open access) Audience Questions (pdf)
  • Regulation of Drug Transport Proteins – From Mechanisms to Clinical Impact
  • In Vitro-In Vivo Correlation for Drug-Drug Interactions with Rosuvastatin
  • Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations
  • FDA’s Final DDI Guidances What You Need to Know About Transporter DDI
  • Use of Extended Clearance Concept and PBPK Modeling in New Drug Discovery and Development: Predicting Target Tissue Exposure from In Vitro to In Vivo (open access) Presentation Slides (pdf)
  • Proteomics-Informed Prediction of Transporter-Enzyme Interplay in Drug Disposition
  • Novel Insights into the Etiology and Treatment of Drug-Induced Peripheral Neuropathy
  • Intestinal OATP mediated Drug Interactions: Where are We
  • Amino Acid Transporters as Potential Targets in Cancer Therapy
Past White Papers
We encourage you to review the International Transporter Consortium (ITC) white papers below that were published in Clinical Pharmacology & Therapeutics (CPT) in 2022. To access the digital versions, please visit your Member Dashboard and click on CPT Member Access. You can then search for them by their titles.
  = open access

KWK Cheung

Kit Wun Kathy Cheung, PharmD

Community Chair


X Yang

Xinning Yang, PhD

Community Co-Vice Chair


Mary Paine

Mary Paine, PhD

Community Co-Vice Chair


J Sprowl

Jason Sprowl, PhD

Community Past Chair


Steering Committee
Vikram Arya, PhD
Shuiying Hu, PhD
Yang Li, PhD
Xiaomin Liang, PhD
Sook Wah Yee, PhD
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