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January 2020: New Member Profile

Author: [AUTHOR] Published on 1/1/2020 12:00:00 AM

New Member V Ayyar
Vivaswath Ayyar, PhD, Janssen Pharmaceuticals, Lansdale, PA

In May 2019, Dr. Ayyar received his PhD in Pharmaceutical Sciences from the University at Buffalo. He worked in Dr. William Jusko's group and his research focused on the combined application of experimental, theoretical, and systems pharmacology modeling approaches to delineate major drug‐ and system‐specific determinants of corticosteroid PK/PD. Dr. Ayyar decided to join ASCPT to expand his professional network and to become more deeply involved within the communities of clinical pharmacology and translational science. During his training at University at Buffalo he closely followed the ASCPT journal family. Clinical Pharmacology & Therapeutics and CPT: Pharmacometrics & Systems Pharmacology especially were helpful to him. When he became a PK/PD Scientist at Janssen Pharmaceuticals, he learned about the numerous benefits of becoming an ASCPT member from multiple colleagues in his research group. The Discovery & Translational Research group's Senior Director, Dr. Donald Heald, encouraged Dr. Ayyar to join ASCPT.

Dr. Ayyar is a dual member with ASCPT and ISoP and he believes that his memberships will “work in synergy” to help him achieve his professional goals. He specifically looks forward to broadening his scientific perspectives in the translational and clinical sciences. He believes his membership will allow him to connect with early‐stage and experienced professionals in the field. He hopes to assume leadership opportunities that enable him to make a positive impact by giving back to the community. Access to the three journals, the frequent webinars, volunteer opportunities, and Annual Meeting attendance are particularly appealing to Dr. Ayyar. He has already become involved in the Early Career Community and has served as a proposal reviewer for the ASCPT 2020 Annual Meeting.

The translational sciences, including the areas of biomarker discovery, PK/PD, and model‐based drug development, play a vital role in realizing precision medicine and empowering the “bench‐to‐bedside” (and vice versa) paradigms of therapeutic discovery and patient care. At Janssen, Dr. Ayyar's research involves the design and application of mathematical models to guide and inform the development and translation of novel biotherapeutics by leveraging both preclinical and clinical data. In addition to his work at Janssen, Dr. Ayyar is serving as an Adjunct Assistant Professor at UB where he continues his research to understand the complex mechanisms of corticosteroid actions utilizing mechanistic and systems modeling approaches.

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