Author: [AUTHOR] Published on 6/14/2023 12:00:00 AM

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CALL FOR PAPERS

Clinical Pharmacology & Therapeutics (CPT) is inviting submissions for a special themed issue on “Getting the Dose Right”
 
Dose-finding, or “getting the dose right”, is central to the role of clinical pharmacology throughout the development and clinical use of therapeutics. Recently, its fundamental place has been given further emphasis with the launch by the US Food and Drug Administration of Project Optimus, highlighting the importance of getting the dose right in oncology. And it remains critically important in all other therapeutic areas to ensure patient benefit without unnecessary adverse effects.
 
Areas of interest for this issue include, but are not limited to:

• Getting the dose right in all therapeutic areas
• Getting the dose right during drug development and in clinical practice
• Getting the dose right for populations and for individual patients
• Getting the dose right for new indications of existing medications currently used at a different dose
• Drugs of all modalities and/or routes of administration
• The use of biomarkers and/or novel analytical methods to help get the dose right
• Getting the dose right for drug combinations
• Optimal trial designs to get the dose right
• Using real world data to find the right dose
• The importance of getting the dose right for patients, prescribers, regulators, payers and/or drug developers
• The use of model-informed drug development (MIDD) and model-informed precision dosing (MIPD) to get the dose right
• The use of artificial intelligence (AI) and machine learning (ML) to get the dose right
• Getting the dose right through clinical deployment of translational systems pharmacology models

Submissions of original research are particularly encouraged, but reviews, position/white papers, or shorter perspectives are also welcome. Educational, tutorial-style papers will also be considered. 

In the cover letter of your submission, please state that you are responding to this Call for Papers. Please contact cpteditor@ascpt.org for details about manuscript types and format requirements, or review our Author Guidelines here.

To be considered for publication in this high-profile themed issue, manuscripts should be submitted via the online submission and tracking system by February 1, 2024.

If you would like to make a pre-submission inquiry, please contact the CPT editorial office at cpteditor@ascpt.org.