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Celebration of Translation at the ASCPT 2019 Annual Meeting

Author: John A. Wagner, MD, PhD on April 24, 2019

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Congratulations to the American Society for Clinical Pharmacology and Therapeutics (ASCPT), Dan Hartman, MD, President, the Scientific Program Committee, chaired by Piet van der Graaf, PhD, PharmD, and all of the speakers, contributors, exhibitors, staff, and attendees for a fantastic 2019 Annual Meeting in March. It should come as no surprise given the theme of “From Molecule to Patient” that much of the meeting was focused on translation. The terrific content is too abundant to detail here, but included more than 300 scientific posters, State of the Art Lectures, Symposia, Workshops, Science at Sunrise, the Innovation Forum, and a new format this year, a Patient Forum. 

Translational medicine was at the center of some of the scintillating sessions at the Annual Meeting. State of the Art Lectures – always excellent – took three different perspectives on “From Molecule to Patient:” 

1) From Molecule to Patient:  A Global Health Perspective by Penny Heaton, MD, Gates Medical Research Institute;

2) A New Science of Therapeutics for Undruggable Targets by Jay Bradner, MD, Novartis Institutes for Biomedical Research; and

3) From Molecule to Patient:  A Biotech Perspective by Robert Langer, Jr., ScD, Massachusetts Institute of Technology. 

The Innovation Forum was also a big hit this year including conversations with Niven Narain, PhD, BERG, Lara Mangravite, PhD, Sage Bionetworks, Pratik Shah, PhD, Massachusetts Institute of Technology Media Lab, and Adrian Krainer, PhD, Cold Spring Harbor Laboratory. A new format called the Patient Forum totally hit it out of the park including moving presentations bridging innovation and the needs and perspectives of patients, including David Fajgenbaum, MD, MBA, University of Pennsylvania, Pujita Vaidya, MPH, US Food & Drug Administration, Mark Skinner, JD, Institute for Policy Advancement, and Matthew Might, PhD, University of Alabama at Birmingham. 

ICYMI: Many of these terrific presentations are available on ASCPT Replay. In addition, the theme of “From Molecule to Patient” was highlighted by all three ASCPT journals in a virtual issue

Clinical and Translational Science (CTS) welcomes manuscript submissions based on the ASCPT Annual Meeting. Every year the Annual Meeting precipitates impactful content in CTS. In fact, some of our most impactful articles originated from Annual Meeting content, including Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities with 60 citations. A key aim of CTS is to be a beacon and organizing principle for the field of translational medicine, which is a major focus of ASCPT. The journal highlights original research that helps bridge laboratory discovery with the diagnosis and treatment of human disease, consistent with the intent of much of the content of the Annual Meeting. CTS welcomes high quality, scientifically sound original manuscripts focused on clinical pharmacology and translational science, including animal, in vitro, in silico, and clinical studies supporting the breadth of drug discovery, development, regulation and clinical use of drugs. 

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