Translational Bytes

May30 Will Blocking Tryptase Treat Asthma?

Despite multiple available therapies, many patients with asthma still have symptoms that are not well controlled. Most current therapies for asthma target mediators of type 2 inflammation (e.g., interleukins), but these therapies do not provide adequate relief for many patients with type 2-independ...

There is a high prevalence of mental illness and substantial utilization of psychoactive prescription drugs (including antidepressants) among Americans. Given the bidirectional relationship between mental illness and other chronic medical conditions, it is very common for persons with a mental illn...

Federal funding is great, but it takes more than money to translate innovative research ideas into the clinic where they can impact public health. The National Cancer Institute's Small Business Innovation Research Development Center (NCI SBIR) supports the commercialization of novel cancer-related ...

Apr19 Drugs and Bugs

Clinical pharmacology is often viewed as what a drug does to the body and what the body does to a drug. On and in our bodies is a universe of microbes, and each microorganism has its own cellular machinery that can interact with drugs, too. However, the trillions of cells that make up an in...

Mar30 CTS Around the World

Clinical and Translational Science ( CTS ) strives to publish high-quality research from across the globe. But how are we doing, and how can we do more? In 2022, half of all accepted manuscripts were submitted by authors from countries other than the USA. Most of these manuscripts came from Eu...

Searching and compiling information from unstructured text is improving, but still presents barriers in navigating between data sources and publications. As a result, information that aids in answering translational questions can hide in plain sight within a corpus of published research and siloed ...

Feb14 Wearing Your Safety Monitor

The FDA has recently approved several wearable technologies for monitoring at-home, including continuous glucose monitoring devices. Historically, clinical glucose monitoring has been carried out using either a finger prick or venipuncture, in which the sample is eventually evaluated by a specializ...

A recent review from The Lambert Initiative of Cannabinoid Therapeutics, published in Clinical and Translational Science ( CTS ), evaluated the efficacy and safety of oral CBD, at doses less than or equal to 400 mg per day in adults.

Looking back at 2022, CTS has celebrated much success. One of our goals continued to be becoming a beacon for the field of translational science, fulfilling a major component of ASCPT’s strategic plan. Growth of CTS since we relaunched as an ASCPT journal in 2016 is displayed in the graph a...

An increasing number of studies have reported using natural language processing (NLP) to assist observational research by extracting clinical information from electronic health records (EHRs). Currently, no standardized reporting guidelines for NLP-assisted observational studies exist. The absence ...

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