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Webinar Resources

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ASCPT Webinar Presented by the International Transporter Consortium
Title: Use of Extended Clearance Concept and PBPK Modeling in New Drug Discovery and Development: Predicting Target Tissue Exposure from In Vitro to In Vivo
Date and Time: Wednesday, March 31, 2021, 5:00-6:30 pm ET
Speaker: Yuichi Sugiyama, PhD, RIKEN Baton Zone Program
Description: Join us for a special 90-minute webinar with guest speaker Yuichi Sugiyama, PhD, as he officially kicks off the April 19-21, 2021, International Transporter Consortium Workshop 4. Professor Sugiyama will describe “Extended clearance concept” and show participants how to establish a physiologically- based pharmacokinetic (PBPK) model that includes the transporter-mediated membrane transport and enzyme-mediated metabolism processes. In addition, changes in transporter (influx, efflux) function and metabolizing enzyme function affects the pharmacokinetics of drugs in the blood and the liver and, ultimately, the pharmacological and/or toxicological effects will be discussed. Related to the above-described objectives, the webinar will also cover recent studies on the following three topics.
  1. Necessity of incorporating albumin-mediated hepatic uptake mechanism to obtain better in vitro/in vivo extrapolation of hepatic clearance.
  2. Substrate-dependent and/or pre-incubation time dependent Ki values of OATP1B inhibitors.
  3. Use of endogenous biomarkers to facilitate subject phenotyping and DDI Prediction.
Registration Link: 
https://us02web.zoom.us/webinar/register/WN_OG3ln41GTiitYyas8zHLfw

*Note: registration for this special webinar is open and participants are encouraged to register for the International Transporter Consortium Workshop 4 being held April 19-21, 2021.

ASCPT Career Center Micro-Recruitment Session with the Certara’s Mark Lovern, PhD
Date and Time: Wednesday, May 5, 2021, 11:00 am EST
Speaker: Mark Lovern, PhD
Description: Have you ever wondered what a career as a drug development consultant is like? If so, please join this session with Mark Lovern, PhD, Senior Vice President of Quantitative Science Services at Certara. Mark will provide a general overview of the software and services that Certara supports. Then, he’ll discuss what it’s like to work as a pharmacometric or clinical pharmacology consultant in a fast paced, global organization. At the end of the presentation, there will be a Q&A session. Join us to learn if you’d be a good fit for the growing Certara team!
Register Now!

Mission
To facilitate ASCPT member engagement in the science and practice of clinical pharmacology beyond the Annual Meeting through the development of an ongoing webinar series.
Responsibilities
The ASCPT Webinar Committee is responsible for reviewing, coordinating, and scheduling of select ASCPT Members-Only Webinars. Representatives from each of the three ASCPT Networks are included in the Committee and are charged with facilitating the submission of high-quality proposals from their respective Networks.

Eric Masson, PharmD

Committee Chair

Webinar committee D M Smith

D. Max Smith, PharmD

Committee Vice Chair

Kimberly Collins, PhD

Committee Past Chair

Committee Members
Manoranjenni Chetty, PhD
Daniel Kirouac, PhD
Malek Okour, PhD
Tore B. Stage, PhD
Bianca D. Van Groen, PharmD

Webinar proposals are received and reviewed by the Webinar Committee on an ongoing basis. Please plan to submit your completed proposal using the form below at least 8 weeks prior to your planned webinar. Note, based on the current Webinar schedule, your desired date(s) may be unavailable, however, the Webinar Committee will review to select alternate options.

Submit a Webinar Proposal

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  • No webinars are scheduled in February or March due to the Annual Meeting
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  • Encore Annual Meeting content and Annual Meeting-related proposals will not be reviewed or accepted until after the Annual Meeting.
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